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患者男性,37岁。因咳喘1天,于1991年9月19日下午到某医院就诊。既往体健,有肌注氨基比林后出现皮肤搔痒的病史。体检:一般状态好。咽红,充血。心肺正常,肝脾不大。诊断为上呼吸道感染。予以肌注庆大霉素(成都军区制药四厂,批号900206)8万单位,约1分钟后患者出现面色苍白、烦燥不安,继之颈项后仰,双眼发直,不能言语,呼吸极度困难,面色青紫,心音微弱不清。立即心内注射肾上腺素1mg 并行人工呼吸,数分钟后瞳孔散大,心跳呼吸停止。于肌注庆大霉素后8分钟内死亡。本例为上呼吸道感染患者,用庆大霉素前一般状态良好,于肌注庆大霉素后立即发生严重过敏性休克反应并迅速死亡,其临床表现与青霉素所引起的过敏
Male patient, 37 years old. Due to cough and asthma for 1 day, on the afternoon of September 19, 1991 to a hospital. Past physical health, there is a history of skin itch after intramuscular aminopyrine. Physical examination: the general state is good. Throat, congestion. Cardiopulmonary normal liver and spleen is not. Diagnosis of upper respiratory tract infection. To be intramuscular injection of gentamicin (Chengdu Military Region Pharmaceutical Factory 4, batch number 900206) 80,000 units, about 1 minute after the patient appeared pale, irritable, followed by neck backwards, eyes straight, speechless, breathing extremely difficult , Looking bruising, weak heart sounds. Immediate intra-cardiac injection of epinephrine 1mg parallel artificial respiration, mydriasis after a few minutes, cardiac arrest stopped. After intramuscular injection of gentamicin died within 8 minutes. In this case, patients with upper respiratory tract infection with gentamicin before the general state of good, immediately after intramuscular injection of gentamicin severe anaphylactic shock and rapid death, its clinical manifestations and penicillin-induced allergies