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目的：探讨巨细胞病毒（CMU）感染与慢性肾盂肾炎发病的关系．方法：应用免疫斑点法检测慢性肾盂肾炎患者尿液中CMV，酶联免疫吸附试验检测患者血清中CMV抗体．结果：68例慢性肾盂肾炎患者中36例尿液CMV抗原检测阳性（53％），39例血清CMV抗体阳性（57％）；50名健康对照组尿液CMV抗原阳性4例（8％），血清CMV抗体阳性7例（14％），两组比较，差异有非常显著意义（P＜0.01）．结论：提示CMV感染可能是肾盂肾炎病因中的一个重要因素．
Objective: To investigate the relationship between cytomegalovirus (CMU) infection and chronic pyelonephritis. Methods: The CMV in urine of patients with chronic pyelonephritis was detected by immunofluorescence assay. The serum CMV antibodies were detected by enzyme - linked immunosorbent assay (ELISA). Results: In 68 cases of chronic pyelonephritis, 36 cases were positive for CMV antigen (53%) and 39 cases were positive for CMV (57%). Urinary CMV antigen was positive in 4 cases (8%) in 50 healthy controls, Serum CMV antibody positive in 7 cases (14%), the two groups, the difference was significant (P <0.01). Conclusion: It is suggested that CMV infection may be an important factor in the etiology of pyelonephritis.