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目的了解郑州铁路局职工高尿酸血症(HUA)流行现状和影响因素。方法以2014年5月-2014年8月在郑州铁路疾病控制预防所参加体检的郑州铁路局职工4 916人为研究对象,应用现况研究和病例对照研究方法,分析郑州铁路局职工高尿酸血症患病率及其危险因素。结果高尿酸血症总患病率为24.3%,标化患病率为18.8%;男性、女性患病率分别为26.3%、10.9%,差异具有统计学意义(χ2=70.6,P<0.01)。高尿酸血症的危险因素有高血压、高甘油三脂、高胆固醇和低高密度脂蛋白胆固醇,其OR(95%CI)分别为1.42(1.22~1.65)、2.53(2.18~2.93)、1.69(1.28~2.22)和1.23(1.08~1.38)。结论郑州铁路局职工高尿酸血症患病率男性高于女性,高血压、高甘油三脂、高胆固醇、低高密度脂蛋白胆固醇和HUA的发生密切相关。
Objective To understand the prevalence and influencing factors of hyperuricemia (HUA) in Zhengzhou Railway Administration. Methods A total of 4 916 employees of Zhengzhou Railway Bureau participated in the physical examination of Zhengzhou Railway Disease Prevention and Control Center from May 2014 to August 2014 as the research object. The status quo and case-control study methods were used to analyze the prevalence of hyperuricemia in Zhengzhou Railway Bureau Prevalence and risk factors. Results The prevalence of hyperuricemia was 24.3% and the standardized prevalence was 18.8%. The prevalence rates of males and females were 26.3% and 10.9% respectively, with significant difference (χ2 = 70.6, P <0.01) . The risk factors for hyperuricemia were hypertension, hypertriglyceridemia, hypercholesterolemia and low-density lipoprotein cholesterol. The OR (95% CI) were 1.42 (1.22-1.65), 2.53 (2.18-2.93) and 1.69 (1.28-2.22) and 1.23 (1.08-1.38). Conclusion The prevalence of hyperuricemia among workers in Zhengzhou Railway Bureau is higher than that in males, hypertension, triglyceride, high cholesterol, low-density lipoprotein cholesterol and HUA.