Lack of correlation between rejection of tumor cells co-expresssing interleukin-2 and B7.1 and vacci

• 作 者: G.Richter S.Cayeux C.Becker C.
• 机 构: Max-Delbrck-CenterforMolecularMedicine,Robert-Rssle-Strasse10,13122Berlin,Robert-RssleKlinik,FreieUn
• 出 处: 中国实验血液学杂志
• 发表日期: 1997年3期
• 关键词: REJECTION INTERLEUKIN vaccine immunity expressing cytokines immunized comparable

Gene modification of tumor cells to express a varietyof cytokines such as IL-2 or the co-stimulatory moleculeB7. 1 led to increased immunogenicity and reducedtumorigenicity of tumors has several models and thisprocess involves T cells. We have previously