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本文报告1例肾功能不全患者,用大剂量水溶性碘剂作泌尿系造影后,产生了碘疹。患者,男,52岁,以往身体健康,从未患过变态反应性疾病,未用过含碘的药物,也未接受过含碘的造影剂。入院前有体温稍增高、呕吐、肌肉疼痛和体重下降。入院检查发现血清肌酐增高,随即用相当于14克碘的metrizoate 40毫升作泌尿系造影,未发生并发症,但未见造影剂排出。12天后,在作肾活检的同时,用大剂量显影剂再作泌尿系造影,用相当于45克碘的泛影葡胺120毫升,此时肌酐廓清率每分钟约7毫升,肝功能正常,造影后没有立即出现
This article reports 1 patient with renal insufficiency, with large doses of water-soluble iodine for urography, the resulting iodine. Patient, male, 52 years old, previously healthy, had never had an allergic disease, had not used iodine-containing drugs, and had not received iodine-containing contrast media. Pre-hospital temperature slightly increased, vomiting, muscle pain and weight loss. Admission examination found that serum creatinine increased, then equivalent to 14 grams of iodine metrizoate 40 ml for urography, no complications, but no contrast agent discharge. 12 days later, at the same time as the renal biopsy, with a large dose of developer for urography, with equivalent to 45 g iodine diatrizoate 120 ml, when creatinine clearance rate of about 7 ml per minute, normal liver function, After angiography did not appear immediately