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目的:观察盆底肌按摩治疗对于行体外受精-胚胎移植(IVF-ET)卵巢储备低下患者妊娠结局的影响。方法:将接受IVF-ET的卵巢储备低下患者95例随机分为观察组(50例)、对照组(45例),两组在COH之前均给予人工周期治疗2个周期,观察组同时加用盆底肌按摩治疗。两组患者促排方案均选用改良超短方案。比较两组Gn使用天数,Gn用量,HCG日内膜厚度、类型、获卵数、受精率、卵裂率、优质胚胎率、种植率、妊娠结局。结果:HCG日观察组内膜厚度及A型内膜比例均优于对照组(P<0.05),观察组E2水平高于对照组(P<0.05)。观察组Gn用量低于对照组(P<0.05),获卵数、优质胚胎率、妊娠率均高于对照组(P<0.05)。结论:盆底肌按摩治疗对接受IVF-ET的卵巢储备低下患者的妊娠结局具有积极作用,可提高妊娠率。
Objective: To observe the effect of pelvic floor massage on pregnancy outcome in patients with ovarian reserve who underwent in vitro fertilization-embryo transfer (IVF-ET). Methods: Ninety-five patients with low ovarian reserve receiving IVF-ET were randomly divided into observation group (50 cases) and control group (45 cases). Both groups were given artificial cycle treatment for 2 cycles before COH. Pelvic floor massage treatment. Promote the two groups of patients were selected to improve the short program. The days of Gn use, Gn dosage, HCG endometrial thickness, type, number of oocytes retrieved, fertilization rate, cleavage rate, quality embryo rate, implantation rate and pregnancy outcome were compared between the two groups. Results: The intima-media thickness and ratio of type A endometrium in HCG-day observation group were better than those in control group (P <0.05). The E2 level in observation group was higher than that in control group (P <0.05). The amount of Gn in the observation group was lower than that in the control group (P <0.05), the number of oocytes retrieved, the rate of high quality embryos and the pregnancy rate were higher than those in the control group (P <0.05). CONCLUSIONS: Pelvic floor massage has a positive effect on pregnancy outcome in patients with low ovarian reserve who receive IVF-ET, and can improve pregnancy rates.