Evaluation of safety for hepatectomy in a novel mouse model with nonalcoholic-steatohepatitis

• 作 者: Yusuke Ozawa Takafumi Tamura Y
• 机 构: DepartmentofGastrointestinalandHepato-Biliary-PancreaticSurgery,DepartmentofEndocrinologyandMetaboli
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2018年15期
• 关键词: HEPATECTOMY LIVER REGENERATION RESIDUAL LIVER LIVER proliferation NONALCOHOLIC S
• 基金项目: Supported by Ministry of Education,Culture,Sports,Science,and Technology of Japan,KAKENHI,No.26861059 and No.16K10489.

AIM To investigate whether the liver resection volume in a newly developed nonalcoholic steatohepatitis(NASH)model influences surgical outcome.METHODS For establishment of a NASH model,mice were fed a high-fat diet for 4 wk,administered CCl4 for the last