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目的探讨人绝经期尿促性腺激素(HMG)联合来曲唑治疗对多囊卵巢综合征(PCOS)不孕症患者排卵情况及妊娠率的影响。方法选取2015年3月-2016年3月该院收治的PCOS不孕症患者134例,依治疗方法设对照组与研究组,各67例。对照组予HMG治疗,研究组予HMG联合来曲唑治疗,观察两组排卵情况、妊娠率及生殖激素水平。结果研究组睾酮(T)、黄体生成素(LH)、促卵泡素(FSH)、雌二醇(E_2)水平低于对照组,差异有统计学意义(P<0.05);研究组排卵率与妊娠率86.58%、38.81%高于对照组的58.21%、17.91%,差异有统计学意义(P<0.05)。结论 HMG联合来曲唑治疗PCOS不孕症可改善生殖激素水平及排卵情况,提高妊娠率。
Objective To investigate the effects of menopausal urogenital gonadotropin (HMG) combined with letrozole on ovulation and pregnancy rate in women with polycystic ovary syndrome (PCOS) infertility. Methods From March 2015 to March 2016, 134 patients with PCOS infertility admitted to our hospital were enrolled. According to the method of treatment, the control group and study group were given 67 cases each. The control group was treated with HMG. The study group was treated with HMG combined with letrozole. The ovulation, pregnancy rate and reproductive hormone level were observed in both groups. Results The levels of testosterone, LH, FSH and E2 in the study group were lower than those in the control group (P <0.05). The ovulation rate and pregnancy rate 86.58%, 38.81% higher than the control group of 58.21%, 17.91%, the difference was statistically significant (P <0.05). Conclusion HMG combined with letrozole treatment of PCOS infertility can improve reproductive hormone levels and ovulation, improve pregnancy rates.