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吸烟对牙周组织的影响,可能和改变微循环有关;微循环障碍是牙周炎的主要症状之一。吸烟以后血小板聚集增加,容易形成微血栓。作者用18只豚鼠进行试验,把豚鼠放在充满香烟燻烟的箱内2次,立即在安眠朋钠麻醉下切取龈组织。检查健康人34例(吸烟10年以上16例),轻度和中度牙周炎46例(不吸烟,无全身病),年龄35～50岁,进行龈组织活检。龈组织抗血小板聚集活性的评定:利用二磷酸腺甙诱导血小板聚集的作用,取富有血小板的血浆1.5ml,加入称量龈组织孵育10分钟(22℃),计算龈组织抑制二磷酸腺甙诱导血小板聚集的程度。聚集图指
The effects of smoking on periodontal tissue may be related to changes in microcirculation; microcirculation is one of the main symptoms of periodontitis. After smoking increases platelet aggregation, easy to form microthrombus. The authors tested with 18 guinea pigs, guinea pigs in a box filled with cigarette smoke 2 times, immediately under anesthesia in the sleep Yin gingival tissues. A total of 34 healthy subjects (16 cigarettes smoked for more than 10 years), 46 mild and moderate periodontitis (no smoking, no systemic disease), and 35 to 50 years old were examined for gingival biopsy. Gingival tissue anti-platelet aggregation activity evaluation: the use of adenosine diphosphate induced platelet aggregation, taking platelet rich plasma 1.5ml, adding weighing gingival tissue incubated for 10 minutes (22 ℃), calculated gingival tissue inhibition of adenosine diphosphate induction The degree of platelet aggregation. Aggregation figure means