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目的探讨海岛不育男性精液质量及其影响因素。方法采用统一调查表,对舟山市生殖研究中心门诊的228例不育症男性患者进行流行病学问卷调查及精液常规分析(SFA);并对数据进行统计学处理。结果研究对象的平均精子密度、a级、b级精子和正常形态精子的百分率分别为23.34×106/ml、35.16%、9.38%和59.27%。对精液质量异常的可能危险因素进行多因素logistic回归分析显示,吸烟:OR=1.169,95%CI=(1.044~1.310);饮酒:OR=1.186,95%CI=(1.055~1.333);不育时间:OR=0.822,95%CI=(0.719~0.940);以蔬菜水果为主要摄入副食类:OR=0.284,95%CI=(0.090~0.894);以混合副食为主要摄入类:OR=0.365,95%CI=(0.175~0.762)。结论研究对象的精子数量、活力和形态基本达到WHO建议的参考值范围,但精子前向运动的能力偏低。吸烟与饮酒行为可能是精液质量的危险因素;副食品摄入类型与精液质量有关,其中,与海产品为主要摄入类型相比,以蔬菜水果类和混合副食品为主要摄入类型的饮食习惯可能对精液质量具有保护作用。
Objective To investigate the quality of semen in infertile men and its influencing factors. Methods A total of 228 male infertility patients in Zhoushan Reproductive Research Center were investigated by epidemiological questionnaire and routine sperm analysis (SFA) using a unified questionnaire. The data were statistically analyzed. Results The average sperm density, a grade, b grade sperm and normal spermatozoa were 23.34 × 106 / ml, 35.16%, 9.38% and 59.27%, respectively. Multivariate logistic regression analysis of possible risk factors of abnormal sperm quality showed that smoking: OR = 1.169, 95% CI = (1.044-1.310); drinking: OR = 1.186,95% CI = (1.055-1.333); infertility OR = 0.284, 95% CI = (0.090 ~ 0.894); The main intake categories of mixed non-staple food are: OR = 0.822,95% CI = (0.719-0.940) = 0.365, 95% CI = (0.175 ~ 0.762). Conclusion The number of sperm, vitality and morphology of the subjects basically reached the recommended reference value range of WHO, but the ability of sperm to move forward was low. Smoking and drinking behaviors may be the risk factors of semen quality. The types of non-staple food intake are related to the quality of semen. Among them, compared with the main types of seafood, vegetables, fruits and mixed foods are the main types of diet Habits may have a protective effect on semen quality.