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54±7岁的14例劳力性心绞痛男性患者,造影证实各例左前降支的近端完全闭塞但由侧支血管逆行充盈并向存活心肌供血。心大静脉血流量由热稀释法测定,并测定心大静脉血氧饱和度。在对照状态下,在心房最快调搏时和在给予潘生丁(在4min 内静脉注入0.56mg/kg)后依次进行测定。每例患者在心房最快调搏时和给予潘生丁后,心电图出现缺血性改变。4例患者在心房最快调搏时 ST 段压低幅度大于给予潘生丁后(1.6±0.5对2.4±1.6mm,P<0.05),
Fifty-four (7) angina patients with angina pectoris at 54 ± 7 years of age were confirmed by angiography to demonstrate complete occlusion of the proximal left anterior descending artery in each case but retrograde filling of the collateral vessels and feeding of viable myocardium. Cardiac vein blood flow was determined by thermal dilution method, and determination of cardiac venous oxygen saturation. In the control state, the measurements were performed sequentially at the fastest pacing of the atria and after the administration of dipyridamole (0.56 mg / kg intravenously over 4 min). Each patient had an ischemic change in the electrocardiogram at the time of the fastest pacing of the atria and after administration of dipyridamole. In the 4 patients, the ST segment depression rate at the fastest atrial pacing was larger than that after dipyridamole (1.6 ± 0.5 vs 2.4 ± 1.6 mm, P <0.05)