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目的总结垂体后叶素、硝酸甘油、奥美拉唑联合治疗肝炎肝硬化并上消化道出血的疗效。方法对62例确诊的肝炎肝硬化并上消化道出血的患者,采用常规禁食、在输血补液等支持治疗的同时,给垂体后叶素、硝酸甘油、奥美拉唑静滴。结果62例患者72h止血者49例,有效率79.0%;心电图出现T波改变者7例为11.3%,其中1例出现胸闷,1例出现心慌,经加快硝酸甘油滴速后,胸闷心慌及T波改变消失。62例患者治愈54例,治愈率87.1%。结论垂体后叶素、硝酸甘油、奥美拉唑联合治疗肝炎肝硬化并上消化道出血的疗效较好,适于在基层医院应用。
Objective To summarize the curative effect of pituitrin, nitroglycerin and omeprazole in the treatment of hepatic cirrhosis and upper gastrointestinal bleeding. Methods Sixty-two patients with cirrhosis and upper gastrointestinal hemorrhage were treated with conventional fasting, and intravenous infusion of vasopressin, nitroglycerin and omeprazole was given while supporting therapy such as transfusion rehydration. Results In 62 patients, hemostasis was performed in 49 cases with an effective rate of 79.0%. Seven cases with T wave changes in electrocardiogram were found in 11.3%. One case had chest tightness and one case had palpitation. After accelerated nitroglycerin drip rate, chest tightness, palpitation and T Wave changes disappear. 62 patients were cured in 54 cases, the cure rate was 87.1%. Conclusion The combination of pituitrin, nitroglycerin and omeprazole is effective in the treatment of hepatic cirrhosis with upper gastrointestinal hemorrhage. It is suitable for the application in primary hospital.