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本题就茵陈蒿合承气汤对实验性急性化脓性胆管炎早期肝胆功能改变影响的研究。结果表明：实验性ＡＳＣ早期ＥＴ含量明显升高而成为ＥＴＭ，合方中药具有明显降低ＥＴ含量的效应，其中的大黄、栀子作用显著；ＡＳＣ早期的ＥＴＭ可使肝功受损导致ＡＬＰ和ＧＰＴ值的升高，合方具有保肝和降低ＡＬＰ和ＧＰＴ的效应；ＡＳＣ早期胆汁分泌量减少，术后３天恢复到正常或高于正常水平，合方增加胆汁分泌量效应显著，作用强于单味药；ＡＳＣ早期可使胆汁中的总胆汁酸、胆固醇、ＨＣＯ３－含量减少，合方可使胆红质分泌量增加和胆固醇下降。
The effect of Yinchenhao Hechengqi Decoction on early hepatobiliary function changes in experimental acute suppurative cholangitis was studied. The results showed that: early experimental ET content of ET significantly increased and become ETM, Chinese herbal medicine has a significant effect of reducing ET content, among which the role of rhubarb, wolfberry fruit is significant; early ASC ETM can cause liver damage led to ALP and GPT With the increase of the value, Hefang has hepatoprotective effect and reduces the effect of ALP and GPT; the early bile secretion of ASC decreases, and returns to normal or higher than normal level in 3 days after operation. The effect of Hefei on the increase of bile secretion is significant and its effect is stronger than Single herb; early ASC can reduce the total bile acid, cholesterol, and HCO3-content in bile, and the combination can increase the secretion of bile and cholesterol.