论文部分内容阅读
机体的微生态环境—巢,包括成骨细胞巢、血管巢以及外周巢;外周巢又包括缺血性巢、原发巢及预转移巢。肿瘤干细胞利用机体的干细胞-巢系统在肿瘤的发生、维持生长、增殖、转移和复发中起着重要作用;它还具有耐受抗肿瘤药物和放射治疗的特性。笔者就上述问题的近年研究进展进行综述。
The body’s micro-ecological environment - nests, including the osteoblastic, vascular nests and peripheral nests; peripheral nests and including the ischemic nests, the primary nests and pre-transfer nests. Tumor stem cells make use of the body’s stem cell-nest system to play an important role in tumorigenesis, growth, proliferation, metastasis and recurrence. Tumor stem cells also have the property of being resistant to antineoplastic agents and radiotherapy. The author summarizes the research progress of the above problems in recent years.