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本文作者对５６例病毒性心肌炎患儿，进行了柯萨奇病毒Ｂ组（ＣｏｘＢ）抗体的检测。其中３２例抗ＣｏｘＢＩｇＭ阳性，阳性率为５７．１％，明显高于对照组（Ｐ＜０．００１）。采用ＥＬＩＳＡ法，对抗ＣｏｘＢＩｇＭ阳性的３２例心肌炎患儿血清中可溶性白细胞介素—２受体（ｓＩＬ－２Ｒ）水平进行了检测。结果表明，ＣｏｘＢ病毒感染的心肌炎患儿ｓＩＬ－２Ｒ水平为６７９．００±３５５．０７Ｕ／ｍｌ，健康同龄组为１５７．８７±１５７．２４Ｕ／ｍｌ，二者相比差异显著（Ｐ＜０．００１）。提示ＣｏｘＢ病毒心肌炎存在细胞免疫紊乱。
The authors examined 56 children with viral myocarditis Coxsackie B virus (CoxB) antibodies. 32 cases were positive for CoxBIgM, the positive rate was 57.1%, which was significantly higher than that of the control group (P <0.001). ELISA method was used to detect the serum soluble interleukin-2 receptor (sIL-2R) level in 32 children with myocarditis positive for CoxBIgM. The results showed that the level of sIL-2R in children with CoxB virus infection was 679.00 ± 355.07U / ml and that in healthy cohorts was 157.87 ± 157.24U / ml, showing significant difference (P <0. 001). Tip CoxB virus myocarditis cellular immune disorder.