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脊索瘤是临床少见、局部侵袭性生长的先天性肿瘤,起源于胚胎脊索残余组织,好发于骶尾部和斜坡、蝶鞍及鞍旁中颅窝等颅底区域。1 临床表现 病程多呈缓慢发展,最常见症状和体征为头痛及单侧或双侧外展神经损害。1.1 鞍部型 肿瘤常累及视神经、视交叉和垂体,可出现视力减退、视野缺损、视乳头原发性萎缩、垂体功能低下。少数可累及下丘脑而出现多饮多尿、肥胖和嗜睡等。
Chordoma is a rare clinical, locally invasive growth of congenital tumors, originated in the embryo spinal cord residual tissue, occur in the sacrococcygeal and slopes, sella and sella cranial fossa and other skull base area. 1 The clinical manifestations of the disease mostly slow development, the most common symptoms and signs of headache and unilateral or bilateral abducens nerve damage. 1.1 Saddle-type tumors often involve the optic nerve, optic chiasm and pituitary, there may be vision loss, visual field defects, optic atrophy, pituitary dysfunction. A few can affect the hypothalamus and appear polydipsia, obesity and drowsiness.