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目的：探讨吡喃阿霉素为主方案治疗难治和复发性急性白血病的疗效。方法：TA、THA和TOAP方案。结果：8例病人中5例达完全缓解，且例部分缓解。结论：吡喃阿霉素为主方案治疗难治和复发性急性白血病有一定疗效，其副作用可以耐受。
Objective: To investigate the efficacy of pirarubimycin as the main regimen in the treatment of refractory and relapsed acute leukemia. Methods: TA, THA, and TOAP schemes. RESULTS: Five of 8 patients achieved complete remission and partial remission. Conclusion: The pirarubimycin-based regimen is effective for the treatment of refractory and relapsed acute leukemia, and its side effects can be tolerated.