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该研究旨在确定肥胖症是否中年后动脉硬化加速的独立预测因子。纳入Whitehall Ⅱ研究受试者男性3789例,女性1383例,平均年龄66岁,均接受颈-股动脉压检测,4年后再次进行测定。一般肥胖状况由体质量指数,中心肥胖由腰围和腰臀比,脂肪含量百分比由身体阻抗来评估。通过线性混合模型,对年龄、性别、种族和平均动脉压进行调整后,所有肥胖症测量指标与主动脉硬化[通过随访的脉搏波传导速度(pulse wave velocity,PWV)较基线增加值来确定]相关。排
The aim of this study was to determine if obesity is an independent predictor of accelerated arterial stiffness after middle age. 3789 males and 1383 females enrolled in the Whitehall II study, mean age 66 years old, were tested for neck-to-femoral arterial pressure and re-measured after 4 years. General obesity status by the body mass index, the central obesity by the waist circumference and waist-hip ratio, the percentage of fat content by body resistance to assess. All obesity measures and aortic sclerosis [adjusted by follow-up pulse wave velocity (PWV) over baseline) after adjusting for age, sex, race, and mean arterial pressure using a linear mixed model] Related. row