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目的:观察中药雾化吸入配合中药内服治疗晚期非小细胞肺癌的临床疗效。方法:将60例晚期非小细胞肺癌患者随机分为治疗组和对照组,每组30例。治疗组采用中药雾化吸入与中药内服结合治疗,对照组采用西医常规姑息治疗。结果:治疗后治疗组肿瘤控制近期疗效(CR+PR+SD)、肺癌相关症状改善、体力指数评分、1年生存率均比对照组高(P<0.05),2年生存率未发现统计学差异。结论:中药雾化吸入配合中药内服治疗晚期非小细胞肺癌,在近期疗效、症状改善、体力改善、1年生存率方面优于单纯姑息治疗,可用于无法继续或拒绝放化疗的晚期非小细胞肺癌患者。
Objective: To observe the clinical efficacy of inhalation of Chinese herbs combined with oral administration of Chinese herbs in the treatment of advanced non-small cell lung cancer. Methods: Sixty patients with advanced non-small cell lung cancer were randomly divided into treatment group and control group, 30 cases in each group. The treatment group was treated with inhalation of Chinese herbs combined with oral administration of Chinese herbs, and the control group was treated with conventional palliative treatment of Western medicine. Results: After treatment, the treatment effect of tumor (CR + PR + SD), lung cancer-related symptoms, physical index score and 1-year survival rate were significantly higher than those of the control group (P <0.05) difference. Conclusion: Chinese medicine nebulized inhalation combined with oral administration of traditional Chinese medicine in the treatment of advanced non-small cell lung cancer is superior to simple palliative treatment in short term efficacy, improvement of symptoms, improvement of physical strength and 1-year survival rate. It can be used in advanced non-small cell Lung cancer patients.