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三苯氧胺(TAM)已广泛用于雌激素受体阳性的绝经期乳腺癌患者的辅助治疗,该药安全、有效、副作用小,但TAM有类似雌激素的作用,可改变绝经期低雌激素的水平,从而使宫内膜发生各种不同的病理变化,但对在服用TAM的同时诱发卵巢肿瘤的报道较少;为探讨乳腺癌患者治疗中TAM可能有引起卵巢增大或发展为卵巢肿瘤的作用,1989年9月1日～1994年11月30日间,选择175例绝经后的乳腺癌患者接受TAM治疗。期间,16例行经
Tamoxifen (TAM) has been widely used as an adjunct to estrogen receptor-positive menopausal breast cancer patients. The drug is safe, effective and has few side effects. However, TAM has an estrogen-like effect and can alter the level of low estrogen in menopause. , resulting in a variety of pathological changes in the endometrium, but less reported in the TAM while inducing ovarian tumors; to explore the role of TAM in breast cancer patients may cause ovarian enlargement or the development of ovarian tumors Between September 1, 1989 and November 30, 1994, 175 patients with postmenopausal breast cancer were treated with TAM. During the period, 16 cases passed