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消化性溃疡治愈后容易复发.如何预防其复发是临床上一个棘手问题.我院1996年5月～1997年10月,对35例经胃镜检查证实已治愈的消化性溃疡患者,应用雷尼替丁预防其复发,取得明显效果.现报道如下:1 资料和方法1.1 一般资料 对住院和门诊收治的消化性溃疡患者70例,随机分为预防组和对照组各35例.病程3a～15a,通过胃镜检查证实原溃疡为良性,有单发或多发.预防组男30例,女5例;年龄18岁～29岁15例,30岁～49岁12例,≥50岁8例.对照组男28例,女7例;年龄18岁～29岁18例;30岁～49岁11例;≥50岁6例.两组均无消化道大出血、幽门梗阻等并发症,并在年龄、性别和临床表现等方面差异不显著(P≥0.05).
Peptic ulcer easily cured after recurrence .How to prevent the recurrence is a clinical problem.Our hospital from May 1996 to October 1997, 35 cases of patients with peptic ulcer confirmed by gastroscopy have been cured, the application of ranitidine Ding prevent its recurrence and achieved significant results are reported as follows: 1 Materials and Methods 1.1 General Information on hospitalized and outpatient treatment of peptic ulcer in 70 patients were randomly divided into prevention group and control group, 35 cases of course of 3a ~ 15a, Gastroscopy confirmed that the original ulcer was benign, single or multiple.Prevention group of 30 males and 5 females, aged 18 to 29 years in 15 cases, 30 years old to 49 years in 12 cases, ≥ 50 years in 8. Control group There were 28 males and 7 females, 18 cases were from 18 years old to 29 years old, 11 cases were from 30 years old to 49 years old, 6 cases were ≥50 years old.The complications of gastrointestinal hemorrhage and pyloric obstruction were not observed in both groups, And clinical manifestations and other aspects of the difference was not significant (P ≥ 0.05).