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虽然卤代烃选择氧化成醛被认为是有机合成中极有用的反应,但迄今关于这一转变的有效方法报导得很少。最近有报道介绍,在相转移催化剂冠醚的存在下,伯卤代烃在六甲基磷酰三胺(HMPT)中可被铬酸钾选择氧化成醛。但冠醚较难制备,价格昂贵,且毒性大。文献[5]报导,聚乙二醇可以摺迭成螺旋结构(1),因此具有类似冠醚的性质,可与金属正离子络合,而此络合正离子可与负离子形成离
Although the selective oxidation of halogenated hydrocarbons to aldehydes is considered to be a very useful reaction in organic synthesis, little has been reported so far as effective methods for this conversion. It has recently been reported that primary halogenated hydrocarbons can be selectively oxidized to aldehydes by potassium chromate in hexamethylphosphoric triamide (HMPT) in the presence of a phase transfer catalyst crown ether. But crown ether is more difficult to prepare, expensive, and toxic. It has been reported in [5] that polyethylene glycol can be folded into a helical structure (1) and therefore has crown ether-like properties and can complex with a metal cation, which can form a negative ion