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目的观察和分析反复体位改变对人体心电图节律的影响。方法 150名志愿者在电动立位转床上进行反复体位改变实验,部分志愿者进行头高位倾斜(head-up tilt,HUT)实验、头低位倾斜(head-downtilt,HDT)实验、下体负压实验、低压缺氧检查、运动心肺功能检查,连续监测和记录心电图,统计并比较不同负荷实验中心电图节律失常的百分数。结果在反复体位改变实验中,23.33%(35/150)的志愿者心电图出现了节律失常,其中7.33%(11/150)出现了房室传导阻滞或阵发性室上速的典型节律改变。反复体位改变实验中心电图节律失常的发生率明显高于HUT实验、HDT实验、下体负压实验、低压缺氧检查和运动心肺功能检查(P<0.01),出现典型节律失常的志愿者在其它5项实验或检查中均未出现。结论一定模式的反复体位改变可引起健康志愿者心电图较高频率的节律失常,并出现房室传导阻滞或阵发性室上速的典型节律改变。这提示反复体位改变实验有可能在航天员和飞行员医学选拔或医学鉴定中得到应用。
Objective To observe and analyze the effect of repeated position changes on the rhythm of human ECG. Methods A total of 150 volunteers were subjected to repeated position changes on an electric stand. Some of the volunteers performed head-up tilt (HUT), head-down tilt (HDT), lower body negative pressure , Hypobaric hypoxia examination, exercise cardiopulmonary function test, continuous monitoring and recording of electrocardiogram, statistics and comparison of electrocardiogram arrhythmia percentage in different load experiment. Results In repeated position change experiments, 23.33% (35/150) of volunteers had arrhythmias, of which 7.33% (11/150) experienced typical rhythm changes in atrioventricular block or paroxysmal supraventricular tachycardia . The incidence of electrocardiographic arrhythmia was significantly higher in repeated position change experiment than in HUT, HDT, hypobaric hypoxia, hypobaric hypoxia and cardiopulmonary exercise tests (P <0.01) Neither experiment nor inspection. CONCLUSIONS: A certain pattern of repeated postural changes can cause higher frequency of rhythm disorders in healthy volunteers and a typical rhythm change of atrioventricular block or paroxysmal supraventricular tachycardia. This suggests that repeated postural change experiments may be applied in the medical selection or medical evaluation of astronauts and pilots.