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长期以来,1型糖尿病(T1DM)的诊断主要依据临床表现,由于胰岛素缺乏而导致的典型的口干、多尿、多饮、体重减轻等“三多一少”症状以及不能被口服降糖药控制的显著高血糖,由于自身免疫因素导致胰岛β细胞功能进行性衰竭而依赖外源性胰岛素治疗。然而,近年来关于1型糖尿病的研究使我们认识到,1型糖尿病的诊断往往并不简单,此次ADA发布首个关于1型糖尿病的立场声明(以下简称ADA声明),对诊断部分做出了重要声明。
The diagnosis of type 1 diabetes (T1DM) has long been based mainly on clinical manifestations, symptoms such as dry mouth, polyuria, polyhydration, weight loss and other symptoms of “three more and a few less” due to insulin deficiency, Significant hyperglycemia, controlled by sugar drugs, relies on exogenous insulin therapy due to the progressive failure of pancreatic β-cell function due to autoimmune factors. However, recent studies on type 1 diabetes have led us to recognize that the diagnosis of type 1 diabetes is often not simple. The ADA released its first position statement on type 1 diabetes (ADA statement) Important statement.