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本文作者先测定多种固体表面吸附水分散体系中的磷脂。合成的卵磷脂含有两个饱和脂肪酸,被高度选择性吸附。此实验结果启示,如果血浆中的磷脂也被吸附在动脉壁,则血浆全饱和卵磷脂(卵磷脂中两个脂肪酸都是饱和的,本文称其为全饱和卵磷脂)的浓度升高可能和动脉粥样硬化有关。用透析法制备纯合成卵磷脂的分散体系,全饱和的二肉豆蔻酰卵磷脂(简称DML)和二软脂酰卵磷脂(简称DPL)被吸附在聚苯乙烯柱的表面。其吸附量随分散体系中脂的浓度升高而增加。随温度升高而减少。与DML和DPL对照,不饱和的卵磷脂二油酰卵磷脂(DOL)和|-软脂酰-2-软脂
The authors first determine a variety of solid surface adsorption of water-dispersed phospholipids. The synthetic lecithin contains two saturated fatty acids that are highly selectively adsorbed. This experimental result suggests that if plasma phospholipids are also adsorbed on the arterial wall, the increase in plasma total saturated lecithin (both saturated fatty acids in lecithin, referred to herein as fully saturated lecithin) Atherosclerosis related. The pure synthetic lecithin dispersion was prepared by dialysis method. The fully saturated dimyristoyl lecithin (DML) and dipalmitoyl lecithin (DPL) were adsorbed on the surface of polystyrene column. The amount of adsorption increases with increasing lipid concentration in the dispersion. Decrease with increasing temperature. In contrast to DML and DPL, the unsaturated lecithin dioleoyl lecithin (DOL) and | -alpha-palmitoyl-2-palmitoyl lipid