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羟基喜树碱(HCPT)是植物类抗癌药,由于它可选择性抑制拓朴异构酶Ⅰ(topoⅠ),干扰DNA复制而逐渐受到重视。最近,我们用羟基喜树碱联合顺铂(PDD),脱氧氟苷(FUDR)组成FHP方案,治疗多种晚期恶性肿瘤,共25例,现报告如下。资料与方法一、...
Hydroxycamptothecin (HCPT) is a plant-based anticancer drug, which has attracted increasing attention due to its ability to selectively inhibit topoI and interfere with DNA replication. Recently, we used hydroxycamptothecin combined with cisplatin (PDD), deoxyfluorone (FUDR) to form a FHP regimen to treat a variety of advanced malignant tumors, a total of 25 cases, are as follows. Data and Methods I...