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为探讨骨髓活检在小儿再生障碍性贫血（简称再障）临床应用的价值，采用骨髓活检改良制片法对88例再障患儿进行骨髓组织学定量分析并与涂片对照；同时对其中30例进行治疗后观察；并对76例进行随访。结果表明：小儿再障诊断符合率和疗效判定骨髓活检高于涂片检查，疗效与骨髓造血组织容量，造血细胞绝对值呈正相关，而与非造血细胞绝对值呈负相关；初检造血组织容量大小与生存期长短有关。结果提示：骨髓活检改良制片法适用于儿童，其可作为小儿再障早期诊断、疗效判定、预后评估的一个客观指标。
In order to explore the clinical value of bone marrow biopsy in children with aplastic anemia (referred to as aplastic anemia), bone marrow biopsy improved preparation method for 88 cases of aplastic anemia in children with bone marrow histological quantitative analysis and smear at the same time, of which 30 Cases were observed after treatment; and 76 cases were followed up. The results showed that the diagnostic accuracy and efficacy of pediatric aplastic anemia, bone marrow biopsy higher than the smear examination, the efficacy and bone marrow hematopoietic tissue volume, the absolute value of hematopoietic cells was positively correlated with the absolute value of non-hematopoietic cells was negatively correlated; initial examination of hematopoietic tissue volume Size and length of life. The results suggest that the modified method of bone marrow biopsy is suitable for children, which can be used as an objective indicator of early diagnosis, curative effect and prognosis evaluation of pediatric aplastic anemia.