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目的分析我市不同人群麻疹抗体水平,探讨有效的麻疹免疫策略。方法随机抽取连云港市某乡镇七个年龄组的流动人口和本地人口,孕妇以及<8月龄婴儿共1000人进行麻疹1gG抗体监测,根据不同人群麻疹抗体结果提出相应的免疫策略。结果本地人群的麻疹1gG抗体阳性率、几何平均浓度(GMC)和保护率明显高于外来流动人群(P<0.05)。<8月龄婴儿和成人群体的抗体阳性率最低,男女性别之间的抗体阳性率没有明显差异(P>0.05)。结论加强免疫和应急接种是控制和消灭麻疹的主要手段。
Objective To analyze the level of measles antibody in different population in our city and to explore effective measles immunization strategy. Methods A total of 1000 floating population, local population, pregnant women and infants aged <8 months were collected randomly from 1 township of Lianyungang for measles 1gG antibody surveillance. Based on the measles antibody results of different populations, the corresponding immunization strategies were proposed. Results The positive rate, geometric mean concentration (GMC) and protective rate of measles 1gG antibody in local population were significantly higher than those in migrant population (P <0.05). The antibody positive rate was lowest in <8-month-old infants and adults, and there was no significant difference in antibody positive rate between male and female (P> 0.05). Conclusion Strengthening immunity and emergency vaccination are the main means to control and eradicate measles.