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目的分析氟喹诺酮类药物临床常见不良反应。方法 50例服用氟喹诺酮类药物产生不良反应患者,对其临床资料进行回顾性分析,对患者的相关数据进行探究。结果 50例患者中男性31例,比例为62%,女性19例,比例为38%;8例患者年龄为20~37岁,30例患者年龄为38~58岁,12例患者年龄为59~70岁;男性患者高于女性患者,年龄在38~58岁的患者较多。而主要不良反应药物则为诺氟沙星以及左氧氟沙星,临床不良反应表现为消化系统、神经系统、循环系统以及泌尿系统等,不良反应发生时间为(2.4±1.2)d,恢复用时为(2.9±1.1)d。结论氟喹诺酮类药物临床不良反应较为常见,为此临床医生需要科学合理的对患者进行用药,从而降低药物的不良反应发生率。
Objective To analyze the common clinical adverse reactions of fluoroquinolones. Methods A total of 50 patients with adverse reactions were treated with fluoroquinolones. The clinical data of the patients were retrospectively analyzed and relevant data of patients were explored. Results Among the 50 patients, 31 were male, accounting for 62% and 19 were female, accounting for 38%. Eight patients were aged from 20 to 37 years, 30 patients were 38 to 58 years old and 12 patients were 59 ~ 70 years old; male patients than female patients, aged 38 to 58 years of age patients more. The main adverse drug reactions were norfloxacin and levofloxacin. The clinical adverse reactions were digestive system, nervous system, circulatory system and urinary system. The time of adverse reactions was (2.4 ± 1.2) days and the recovery time was (2.9 ± 1.1) d. Conclusion Fluoroquinolones clinical adverse reactions are more common, for which clinicians need scientific and rational medication for patients, thereby reducing the incidence of adverse drug reactions.