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尖端扭转型室性心动过速(TdP)是一种模式化的多形性室性心动过速,特征表现为QRS轴周期性偏转(围绕等电位线扭转),其前为一长Q-T间期(图1)。这是先天性或获得性长QT综合征(LQTS)的典型心律失常,由结构、代谢、遗传和药学因素综合交互影响所致。明确的流行病学因素包括性另IJ、电解质失平衡、缺血和延长Q-T间期的药物。TdP的可能机制促发TdP的机制不完全清楚。实验证据表明,复杂众多的离子通道相互作用形成心律失常的基础,加之合适的促发
Torsion-type ventricular tachycardia (TdP) is a pattern of pleomorphic ventricular tachycardia characterized by periodic QRS axis deflection (around the equipotential curve to reverse), followed by a long QT interval (figure 1). This is a typical arrhythmia of congenital or acquired long QT syndrome (LQTS) due to a combination of structural, metabolic, genetic, and pharmacological interactions. Specific epidemiological factors include sex IJ, electrolyte imbalance, ischemia and prolonged Q-T interval of the drug. The mechanism by which TdP may trigger TdP is not completely understood. Experimental evidence shows that the complex interaction of many ion channels to form the basis of arrhythmia, coupled with the appropriate to promote