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目的 了解绝经后妇女身高的变化情况与骨密度关系 ,为骨质疏松的诊断提供依据。方法 对 2 4 6例自然绝经妇女测量身高、体重。用双能 X线吸收法 (DEXA)测定腰椎前后位 L 1～ L 4 ;右侧髋部骨密度。结果 随增龄 ,身高、骨密度 (BMD)均下降。身高在 5 0～ 6 0岁下降最为明显 ,6 0～ 6 5岁略缓慢 ,75～ 80岁再次明显下降。以绝经年限划分 ,在 5～ 1 0年下降最为显著 ,以后渐趋缓 ,其中 2 0～ 2 5年下降最慢。 BMD在 L 2～ 4髋部各部位 ,在 5 0～ 6 0岁下降显著 ,6 5～ 70岁缓慢下降期或趋平稳 ,70岁后均大幅度下降。在绝经后 ,前 1 0年下降显著 ,1 0年后 BMD处在相对慢速下降期 ,在 1 5年后又处于快速下降期。 BMD与身高相关性分析 ,R值 0 .395～ 0 .2 6 5 ,P=0 .0 0 0 ,具显著相关性。依诊断 型 OP标准 ,分为 BMD达到诊断 OP标准组与未达到组 ,用 t检验比较两组的身高 ,P=0 .0 0 2 ,具有统计学意义。结论 绝经后 ,妇女 BMD与身高随增龄而下降 ,各部位骨丢失速率存在差异 ,下降的BMD与身高具有相关性
Objective To understand the relationship between the changes of height and bone mineral density in postmenopausal women and to provide basis for the diagnosis of osteoporosis. Methods Height and weight were measured in 246 women with natural menopause. The anterior and posterior lumbar vertebra L 1 ~ L 4 were measured by dual energy X-ray absorptiometry (DEXA). The right hip BMD was measured. Results with age, height, bone mineral density (BMD) decreased. The height was the most obvious decline in 50 ~ 60 years of age, 60 ~ 65 years slightly slower, 75 to 80 years old again significantly decreased. According to the years of menopause, the decline was the most significant in 5 ~ 10 years and then gradually slowed down, of which the decline was the slowest in 20 ~ 25 years. BMD decreased significantly from 50 to 60 years old in all parts of L 2 ~ 4 hips, decreased slowly or slowly from 65 to 70 years old, and decreased significantly after 70 years of age. After menopause, the decline in the previous 10 years was significant. After 10 years, the BMD was at a relatively slow decline and was rapidly declining after 15 years. BMD and height correlation analysis, R value 0 .395 ~ 0 .255, P = .0 0 0, with significant correlation. According to the diagnosis of OP standard, BMD was divided into diagnostic OP group and non-standard group, t-test was used to compare the height of the two groups, P = 0.002, with statistical significance. Conclusions After menopause, the BMD and height of women decreased with age, and there was a difference in the rate of bone loss among the groups. The decreased BMD was correlated with height