【摘 要】
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Nanoparticle-based nucleic acid thera-peutics have drawn considerable attention over recent decades.By using terms such as ‘nanoparticle’ and ‘gene delivery
【机 构】
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Laboratory of Aging Research and Nanotoxicology,State Key Laboratory of Biotherapy, National Clinica
论文部分内容阅读
Nanoparticle-based nucleic acid thera-peutics have drawn considerable attention over recent decades.By using terms such as ‘nanoparticle’ and ‘gene delivery’ in a PubMed search,we found that 10 years ago throughout 2008 there were only 725 such papers published;however,in 2017,over 4700 papers were published with the same keywords.The dramatic increase in the number of publications indicates that the field of nanoparticle-based nucleic acid therapeutics,which is a complicated one underpinned by the development of numerous related fields,such as pharmaceutics,material sciences,immunology and cell biology,is thriving.
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