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免疫印迹和盐裂皮肤间接免疫荧光检测 ５例大疱性系统红斑狼疮（ＢＳＬＥ）血清，对照为 ５例获得性大疤性表皮松解症（ＥＢＡ）、２０例类天疱疮（ＢＰ）、２０例ＳＬＥ和１０例正常人血清。结果表明，３例（３／５）ＢＳＬＥ血清结合盐裂皮肤真皮侧和真皮提取物中２９０ ０００抗原，其中２例ＢＳＬＥ血清也结合表皮提取物中 １６５ ０００抗原，结果与 ＥＢＡ和部分ＢＰ血清相同。ＳＬＥ血清未结合 ２９０ ０００和 １６５ ０００抗原。提示ＢＳＬＥ血清中存在ＥＢＡ和ＢＰ抗体，推测ＥＢＡ和ＢＰ抗原可能是ＢＳＬＥ的皮肤基底膜带相关抗原。
Five cases of BSLE serum were detected by immunoblotting and indirect immunofluorescence staining of the skin with salivary spondylosis. Five cases of acquired epidermolysis bullosa (EBA), 20 cases of pemphigoid (BP) 20 cases of SLE and 10 cases of normal human serum. The results showed that 3 (3/5) BSLE serum combined with 290 000 antigens in the dermal side and dermal extracts of the saliv skin, and 2 of the BSLE sera also bound 165 000 antigens in the epidermal extracts, with the same results as EBA and some of the BP sera . SLE serum did not bind 290 000 and 165 000 antigens. It is suggested that there are EBA and BP antibodies in BSLE serum. It is speculated that EBA and BP antigens may be skin basement membrane associated antigens of BSLE.