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测定肿瘤标记物有助于估计预后。本文着重阐述CA125在卵巢癌术后管理中的意义和问题要点。 通常CA125的临界值订为35U/ml。临床上假阳性病例(指癌无复发,CA125值在临界值以上)很少,假阴性病例(指癌有复发,CA125值在临界值以下)却有相当数量。因此,监控时有必要考虑术后CA125值。例如35U/ml时假阳性为0%,降至20U/ml时假阳性达29%。有报道,复发病例CA125临界值订在16U/ml,比订在35U/ml发现复发要
Measuring tumor markers can be helpful in estimating prognosis. This article focuses on the significance of CA125 in postoperative management of ovarian cancer and the main points. Normally, the cut-off value of CA125 is 35U / ml. Clinical false positive cases (refer to cancer recurrence, CA125 value above the critical value) is very small, false negative cases (refer to cancer recurrence, CA125 value below the critical value) there is a considerable amount. Therefore, it is necessary to consider postoperative CA125 during monitoring. For example, the false positive rate is 0% at 35 U / ml and the false positive rate is 29% at 20 U / ml. It has been reported that the critical value of recurrence CA125 set at 16U / ml, compared to 35U / ml found in the recurrence to