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目的:探究糖尿病合并甲状腺功能异常患者血清免疫球蛋白,补体的变化和临床意义。方法:随机抽取2012年2月~2017年2月我科室的100例糖尿病患者作为实验1组,同期选取30例糖尿病合并甲状腺功能异常患者作为实验2组,再同期选取100例健康体检者为参照组,采用全自动生化仪对所有研究样本的血清免疫球蛋白水平以及补体水平进行检测,评估研究对象的血清免疫球蛋白水平和补体水平以及各项指标的检测灵敏度和特异度。结果:实验2组患者的血清免疫球蛋白水平以及补体水平显著高于实验1组,P<0.05;另外,实验1组和实验2组患者的血清免疫球蛋白水平以及补体水平明显高于参照组,P<0.05。结论:对糖尿病合并甲状腺功能异常患者的血清免疫球蛋白水平和补体水平进行检测,可有效反映患者血管病变程度,从而进一步的判断患者的疾病发展程度,临床意义显著。
Objective: To investigate the changes and clinical significance of serum immunoglobulin and complement in patients with diabetes and thyroid dysfunction. Methods: A total of 100 diabetic patients in our department from February 2012 to February 2017 were selected as experimental group 1 and 30 patients with diabetes mellitus and thyroid dysfunction were selected as experimental group 2 in the same period. 100 healthy subjects were selected as the reference in the same period Group, using automatic biochemical analyzer on all samples of serum immunoglobulin levels and complement levels were tested to assess the study of serum immunoglobulin levels and complement levels and the detection sensitivity and specificity of the indicators. Results: Serum immunoglobulin levels and complement levels were significantly higher in experimental group 2 than those in experimental group 1 (P <0.05). In addition, serum immunoglobulin levels and complement levels in experimental group 1 and experimental group 2 were significantly higher than those in control group , P <0.05. Conclusion: The detection of serum immunoglobulin levels and complement levels in patients with diabetes mellitus and thyroid dysfunction can effectively reflect the degree of vascular lesions in patients with diabetes, thus further judging the patient’s disease development, clinical significance.