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目的:总结喉接触性肉芽肿的临床病理特点及诊治体会。方法:回顾性分析18例喉接触性肉芽肿患者的临床及病理资料。结果:18例患者均病理检查均呈典型炎性肉芽肿,但有1例见少量异型细胞;15例行手术治疗,初次手术后复发率为60%,复发者再次手术,其中4例术后采取抗胃食管反流治疗,仍有3例复发;3例未手术随访观察者1例自愈,2例观察2~4年病情无明显变化。结论:喉接触性肉芽肿好发于中年男性;根据肉芽肿的特定好发部位及外观,临床诊断不难,但仍应重视病理检查,防止漏诊个别有恶变倾向的病例;本病手术治疗后复发率高,抗胃食管反流治疗的疗效有待进一步考证。
Objective: To summarize the clinicopathological features, diagnosis and treatment of laryngeal contact granuloma. Methods: The clinical and pathological data of 18 patients with throat contact granuloma were retrospectively analyzed. Results: The pathological examination of 18 patients showed typical inflammatory granuloma, but a small number of dysplastic cells were seen in one patient. Fifteen patients underwent surgical treatment. The recurrence rate was 60% after initial surgery, and the recurrence was reoperated in 4 of them There were still 3 cases of relapse after anti-gastroesophageal reflux therapy. One case of 3 cases who did not follow-up was self-healing, and 2 cases showed no significant change from 2 to 4 years. Conclusions: Throat contact granuloma occurs in middle-aged men. According to the specific site and appearance of granuloma, clinical diagnosis is not difficult, but pathological examination should be emphasized to prevent the misdiagnosis of individual cases with malignant transformation. The surgical treatment of this disease After the recurrence rate, anti-gastroesophageal reflux treatment efficacy needs further research.