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flunarizine能够通过血脑屏障,因而在欧洲它被选择为治疗眩晕的钙通道阻断剂。尼膜地平是一种高度亲脂性的钙通道阻断剂,它能够通过血液一外淋巴屏障,因而在没有flunarizine的美国它被推荐为治疗眩晕的钙通道阻断剂。该作者为12名一线药物治疗失败的梅尼埃病患者运用尼膜地
Flunarizine is able to cross the blood-brain barrier and is therefore chosen as a calcium channel blocker in the treatment of dizziness in Europe. Nifedipine is a highly lipophilic calcium channel blocker that passes through the bloodstream to an extralymphatic barrier and is therefore recommended as a calcium channel blocker for dizziness in the United States without flunarizine. The authors used nimotopd for 12 patients with Meniere’s disease who failed first-line drug therapy