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妊娠滋养细胞肿瘤虽不是一种高发病,但在中国和其他东方国家较为多见。它是人体中第一个能单独应用化学药物治愈的恶性实体瘤。它的突破,向人类展示了通过化学治疗根治恶性肿瘤的可能性。妊娠滋养细胞肿瘤(Gestational TrophoblasticNeoplasms,简称 GTN)起源于妊娠滋养层细胞的恶变。其中恶性程度最高的叫做绒毛膜癌(Choriocarc-inoma),简称绒癌;另一种恶性程度较低的叫做恶性葡萄胎(Malignant mole)或侵蚀性葡萄胎(Invasi-ve mole)。恶性葡萄胎100%发生于葡萄胎妊娠的恶变;绒癌则可有不同的来源,其中半数以上发生于葡萄胎后,其余部分继发于流产或足月妊娠之后。截止50年代中期,绒癌曾被认为是人体恶性程度
Although not a high incidence of gestational trophoblastic tumors, but more common in China and other countries in the East. It is the first malignant solid tumor in the body that can be cured with a single chemical. Its breakthrough shows humans the possibility of radicalizing malignant tumors through chemotherapy. Gestational Trophoblastic Neoplasms (GTN) originate from malignant changes in gestational trophoblast cells. One of the most malignant is called Choriocarc-inoma, referred to as choriocarcinoma; the other is less malignant called Malignant mole or Invasi-ve mole. Malignant hydatidiform mole occurs in 100% of hydatidiform mole malignancy; choriocarcinoma may have different sources, of which more than half occurred in hydatidiform mole, the rest secondary to miscarriage or term pregnancy. By the mid-1950s, choriocarcinoma had been considered as a human malignancy