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细胞表面微绒毛和细胞微丝状态与细胞运动密切相关。在人胃癌ＢＧＣ－８２３细胞系体外培养液中加用胃泌素及其受体拮抗剂，发现经胃泌素作用后的ＢＧＣ－８２３细胞微丝紊乱，细胞表面微绒毛多而密集，经Ｌ－３６５２６０作用后则微丝长而粗，排列规则，表面微绒毛少。提示，胃泌素能增强ＢＧＣ－８２３细胞系的运动，可能有促进肿瘤细胞转移的作用，这种作用可被Ｌ－３６５２６０所拮抗。
Cell surface microvilli and cell microfilament status and cell movement are closely related. Gastrin and its receptor antagonist were added to human gastric cancer cell line BGC-823 in vitro, it was found that the gastrodin-induced BGC-823 cells were disordered. The microvilli on the cell surface were more and more dense, -365260 Micro filaments after the role of long and thick, arranged in the rule, the surface less microvilli. Tip, gastrin can enhance BGC-823 cell line motility, may have the role of promoting tumor cell metastasis, this effect can be antagonized by L-365260.