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目的:研究环丙沙星联合思密达保留灌肠治疗细菌性痢疾的临床疗效及不良反应。方法:选取2012年8月~2015年8月在我院诊治的细菌性痢疾患者144例,将其依据随机方式划分为对照组和观察组,各组为72例;对照组采取常规治疗方法实施治疗,观察组则在其治疗基础上采用环丙沙星联合思密达实施保留灌肠治疗,就两组患者临床疗效及不良反应予以对比分析。结果:治疗后,观察组、对照组总有效率分别为97.22%、86.11%,两组比较差异明显(P<0.05);观察组不良反应率为0.00%,对照组为6.94%,;两组比较差异显著(P<0.05)。结论:针对细菌性痢疾患者,对其采用环丙沙星联合思密达实施保留灌肠治疗,效果显著,无不良反应,在临床中具有很好推广及应用价值。
Objective: To study the clinical efficacy and adverse reactions of ciprofloxacin combined with Smecta retention enema in the treatment of bacillary dysentery. Methods: A total of 144 patients with bacterial dysentery diagnosed and treated in our hospital from August 2012 to August 2015 were randomly divided into control group and observation group, with 72 cases in each group. The control group was treated with routine treatment The treatment group and the observation group were treated with ciprofloxacin combined with Smectite in the treatment of retention enema on the basis of their treatment, the clinical efficacy and adverse reactions were compared between the two groups. Results: After treatment, the total effective rate in the observation group and the control group was 97.22% and 86.11% respectively, with significant difference between the two groups (P <0.05); adverse reaction rate was 0.00% in the observation group and 6.94% in the control group The difference was significant (P <0.05). Conclusion: For patients with bacillary dysentery, its use of ciprofloxacin combined with Smectite retention enema, the effect was significant, no adverse reactions, has good clinical application and application value.