论文部分内容阅读
本文应用双项间接免疫荧光技术(DIIF)检测孕早期绒毛中的胎儿红细胞,以测定是否存在Rh抗原Rh(D)。人类Rh系统是以孟德尔方式遗传,D阳性高于d.85%欧洲人是D阳性,其中56%D阳性个体是D/d杂合子。D阴性的受累妇女,丈夫是D阳性杂合子,对胎儿Rh抗原D早期的产前诊断,以及妊娠的进一步处理均非常重要。在妊娠前三月末期获取绒毛研究胎儿的红细胞是可行的,与ABO抗原相比,5～6周或晚一些时间胎儿的红细胞能充分表达Rh抗原D。早期检测胎儿的Rh血型,可以发现D阴性或D阳性个体,帮助双亲尽早决定进一步的治疗措施终止妊娠。
In this study, double-labeled indirect immunofluorescence (DIIF) was used to detect fetal erythrocytes in first trimester villi to determine the presence of Rh antigen Rh (D). The human Rh system is inherited in a Mendelian fashion, with a D positive of more than d. 85% of Europeans being D positive and 56% of D positive individuals being D / d heterozygotes. D-negative women involved, the husband is D-positive heterozygotes, early detection of fetal Rh antigen D prenatal diagnosis, as well as further treatment of pregnancy are very important. Obtaining villi to study fetal erythrocytes at the end of the first trimester of pregnancy is viable and the erythrocytes in the fetus are fully expressed at 5 to 6 weeks or later compared to the ABO antigen. Early detection of fetal Rh blood group, you can find D-negative or D-positive individuals, to help parents decide as soon as possible further treatment termination of pregnancy.