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近年来,伤寒的并发症是主要死亡原因之一。自氯霉素应用以来,明显地减轻了伤寒的病情和缩短了病程,但对肠道并发症病理症候学的发生率的减少程度甚低。有资料说明约10～20％的病人应用抗生素无实质性疗效。它不影响小肠的坏死性变化的规律的动态学改变,这是由于特殊的内毒素与自家免疫反应对特异的迟发型过敏性
In recent years, the complication of typhoid fever is one of the major causes of death. Since the application of chloramphenicol, the condition of typhoid fever has been obviously alleviated and the course of disease has been shortened, but the incidence of pathological syndrome of intestinal complications has been reduced to a very low level. There are data that about 10 to 20% of patients with no substantial effect of antibiotics. It does not affect the dynamic dynamics of the law of necrotic changes in the small intestine due to the specific delayed type hypersensitivity to specific endotoxin and autoimmune responses