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趋化因子是一类一级结构相似的小分子蛋白多肽,由70~100个氨基酸组成,可以激活和吸引白细胞及其他免疫细胞,属于细胞因子超家族成员。在所有趋化因子分子中都包含有4个保守的半胱氨酸(C)。根据蛋白质中结构的不同,将它们分为4个亚类:CXC类,亦称为α类趋化因子,如IL-8(Interleukin-8)、MIP-2(巨噬细胞炎性蛋白-2)、SDF-1(基质细胞衍生因子-
Chemokines are a class of small molecule protein peptides with similar primary structure. They consist of 70-100 amino acids and can activate and attract white blood cells and other immune cells and belong to the cytokine superfamily. Four conserved cysteines (C) are included in all chemokine molecules. They are divided into four subclasses based on the structure of proteins: CXC class, also known as class a chemokines such as IL-8 (Interleukin-8), MIP-2 (macrophage inflammatory protein- ), SDF-1 (stromal cell-derived factor-