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朝鲜出血热(KHF)以及在疾病分类学上有关的一些疾病,如流行性出血热、克里米亚出血热和流行性肾病等,都是由田鼠传播于人的农村疾病。KHF的病原——汉坦病毒在生化学上和形态学上类似布尼亚病毒科。在朝鲜,黑线姬鼠是汉坦病毒的主要宿主。慢性感染的黑线姬鼠,可持续地排出病毒尿,一直被认为是导致人类感染的重要机制。然而最近的结果表明:汉坦病毒或与其密切相关的病原可能还有其它的流行病学特征。为此目的,作者对南朝鲜汉城及其附近的4个城市的野鼠作了感染汉坦病毒的调查。本文报道了1977～1979年的初步调查结果,以及从这些鼠中分离到的病原的特征。鼠是从住家中捕获的。处死后,取肺和其它组织冷冻切片,用间接免疫荧光法检
Korean haemorrhagic fever (KHF) and some diseases that are related to the taxonomy of diseases, such as epidemic hemorrhagic fever, Crimean haemorrhagic fever and epidemic nephropathy, are rural diseases transmitted by voles in humans. The pathogen of KHF - the Hantaan virus is biochemically and morphologically similar to Bunyaviridae. In North Korea, Apodemus agrarius is the major host for Hantavirus. Chronic infection of Apodemus agrarius, a sustainable excretion of viral urine, has long been recognized as an important mechanism leading to human infection. However, recent results indicate that there may be other epidemiological features of the Hantaan virus or its closely related pathogens. To this end, the authors investigated the presence of Hantavirus in wild rats in Seoul, South Korea and in four nearby cities. This article reports the preliminary findings from 1977 to 1979 and the characteristics of the pathogens isolated from these mice. The rat is captured from home. After sacrifice, the lungs and other tissues were frozen and sectioned by indirect immunofluorescence