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采用免疫组比方法检测60例手术治疗的垂体腺瘤标本雌孕激素受体．结合内分泌功能分类和临床影像学检查研究ER、PR检测的临床意义。结果表明：垂体腺瘤ER阳性率为77％．PR阳性率为67％。大腺瘤与巨腺瘤ER、PR阳性率低于微腺癌（其中PR组间差异P＜0．05）．ER、PR与垂体腺瘤的侵袭程度相关。
60 patients with pituitary adenomas treated with estrogen and progesterone receptors were examined by immunohistochemistry. The clinical significance of ER and PR detection was studied by combining endocrine function classification and clinical imaging examination. The results showed that the positive rate of ER in pituitary adenomas was 77%. The positive rate of PR was 67%. The positive rate of ER and PR in macroadenomas and giant adenomas was lower than that in microadenocarcinomas (the difference between PR groups was P<0.05). ER, PR and pituitary adenomas are related to the degree of invasion.