论文部分内容阅读
目的分析染色体多态性对生育功能的影响,探讨其与ART妊娠结局的关系。方法回顾性调查分析珠海市妇幼保健院2009年至2010年生殖中心行IVF-ET共1607例患者的染色体核型及其临床资料,研究其ART妊娠情况。结果 1607例生殖异常患者中,检出染色体正常核型1563例(97.3%),ART妊娠877例,妊娠率为56.1%,流产113例,流产率为12.9%;检出染色体多态性核型37例(2.3%),ART临床妊娠20例,妊娠率为54.1%,流产2例,流产率为10.0%。结论染色体正常组与染色体多态性组ART的妊娠率及流产率的差异无显著性统计学意义,染色体多态性患者不影响ART妊娠结局。
Objective To analyze the effect of chromosome polymorphism on reproductive function and to explore its relationship with ART pregnancy outcome. Methods A retrospective survey was conducted to analyze the karyotypes and clinical data of 1607 IVF-ET patients in the reproductive center between 2009 and 2010 in Zhuhai Municipal MCH and their clinical data. Results Among 1607 cases of genital abnormalities, 1563 cases (97.3%) were detected with normal chromosomal karyotype, 877 ART pregnancies, pregnancy rate was 56.1%, abortion was performed in 113 cases and abortion rate was 12.9%. Chromosome polymorphism karyotype 37 cases (2.3%), ART clinical pregnancy in 20 cases, the pregnancy rate was 54.1%, 2 cases of abortion, abortion rate was 10.0%. Conclusion There is no statistically significant difference in pregnancy rate and abortion rate between ART group and chromosomal polymorphism group. The patients with chromosomal polymorphism do not affect ART pregnancy outcome.