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目的:用均匀设计优选半夏白术天麻汤的半仿生提取工艺。方法:采用UL(91×33)均匀试验设计表,以天麻素、甘草次酸、HPLC总面积、总黄酮、相对分子质量≤1 000的提取物为指标综合评判,优选半夏白术天麻汤半仿生提取的工艺条件。结果:3煎用水的pH依次为2.00,6.56,8.73;3煎总计时间为4.92 h。结论:结合生产实际,确定3煎用水的pH依次为2.0,6.5,8.5;提取时间依次为2.0,1.5,1.5 h。
Objective: To optimize the semi-bionic extraction of Banxiabaizhu Tianma Decoction with uniform design. Methods: The uniform design of UL (91 × 33) was used to evaluate the effects of gastrodin, glycyrrhetinic acid, total HPLC, total flavonoids and the relative molecular mass less than 1 000 as the index. Bionic extraction process conditions. Results: 3 fried water pH followed by 2.00,6.56,8.73; 3 fried total time of 4.92 h. Conclusion: According to the actual production, the pH of fried water is determined to be 2.0, 6.5 and 8.5, and the extraction time is 2.0, 1.5 and 1.5 h respectively.