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采用酶联免疫吸附试验(ELISA),对78例因人工流产后所引起的不孕症、140例非人工流产不孕症以及28例正常已婚育龄妇女进行血清抗精子抗体检测。结果:人工流产后不孕组、非人工流产不孕组及正常组抗精子抗体的阳性率分别为33.33%,15.71%,3.57%。人工流产后不孕组血清中抗精子抗体的阳性率显著高于非人工流产不孕组和正常已婚育龄妇女(P<0.05)。提示:由人工流产后所引起的不孕症,在某些方面可能与免疫因素有关。子宫内膜的破损和炎症可能是抗精子抗体产生的一个重要诱因。
Serum anti-sperm antibodies were detected in 78 women with infertility caused by induced abortion, 140 cases of non-abortion infertility and 28 normal women of childbearing age by enzyme-linked immunosorbent assay (ELISA). Results: The positive rates of antisperm antibody in infertility group, non-abortion infertility group and normal group were 33.33%, 15.71% and 3.57% respectively. The positive rate of antisperm antibody in the infertile group after abortion was significantly higher than that in non-abortion infertility group and normal married women (P <0.05). Tip: infertility caused by induced abortion, in some ways may be related to immune factors. Endometrial damage and inflammation may be an important cause of anti-sperm antibody production.