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为了解急性心肌梗塞(AMI)作溶栓治疗时,由于生物反馈机制,血栓溶解凝血酶元活性是否增加,作者观察AMI患者55例,其中35例用尿激酶——预先激活的前尿激酶,20例用组织型胞浆素原活化剂溶栓治疗,在90min和在24～36h血栓溶解时行冠脉造影,并测定纤维蛋白原(Ratnoff-Menzie法)、D一二聚物(ELISA法)和凝血酶——抗凝血酶Ⅱ复合物水平(ELISA法)。结果:有39例(70.9%)患者冠状动脉再通,其中13例(33.3%)发生早期再梗塞。观察到纤维蛋白原水平无明显减少,而D-二聚物水平增加了3.008
In order to understand whether AMI thrombolytic therapy, due to biofeedback mechanism, thrombolytic activity of thrombin element increases, the authors observed 55 cases of AMI patients, of which 35 cases of urokinase - pre-activated pro-UK, Twenty patients were treated with thrombolytic therapy with tissue-derived plasminogen activator. Coronary angiography was performed at 90 min and at 24-36 h thrombolysis. The levels of fibrinogen (Ratnoff-Menzie method), D-dimer (ELISA method ) And thrombin-antithrombin II complex level (ELISA method). Results: Coronary recanalization occurred in 39 patients (70.9%), of which 13 (33.3%) developed early reperfusion. No significant decrease in fibrinogen level was observed, but D-dimer level was increased by 3.008