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目的分析四川口岸首例输入性三日疟感染病例的临床表现及实验室检测结果,为四川地区三日疟的预防控制提供参考依据。方法对2017年四川口岸1例疟疾患者采集血样,采用BinaxNow疟疾快速诊断试剂盒、瑞吉染色镜检和实时荧光PCR方法进行鉴定。结果疟疾快速诊断试剂盒检测患者血样为除恶性疟原虫以外的间日疟原虫、三日疟原虫或卵形疟原虫感染;血涂片镜检为三日疟原虫,密度为2 400/μl;实时荧光PCR检测三日疟原虫核酸阳性。结论结合血涂片、PCR等检测结果、流行病学资料和临床表现,该患者确诊为输入性三日疟原虫感染病例。提示应加强疟防专业人员三日疟诊治技能培训,以减少误诊误治。
Objective To analyze the clinical manifestations and laboratory test results of the first case of imported malaria invade in Sichuan and provide a reference for the prevention and control of malaria in Sichuan Province. Methods Blood samples were collected from 1 malaria patient in Sichuan Port in 2017. The samples were identified by BileuxNow malaria rapid diagnosis kit, Stichting microscopy and real-time fluorescence PCR. Results The malaria rapid test kit was used to detect blood samples of patients with Plasmodium vivax, Plasmodium malariae or Plasmodium ovale other than Plasmodium falciparum; blood smear microscopy was Plasmodium malaria at a density of 2 400 / μl ; Real-time fluorescence PCR detection of Plasmodium malariae nucleic acid positive. Conclusion Combined with blood smear, PCR test results, epidemiological data and clinical manifestations, the patient was diagnosed as imported cases of Plasmodium malariae infection. It is suggested that malaria prevention and treatment professionals should be trained in the diagnosis and treatment of malaria three days to reduce misdiagnosis and mistreatment.